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Grp94 Inhibitor-2

Grp94 Inhibitor-2 (compound 23) is a cyclopropane-containing small molecule that selectively binds Grp94 (Kd=0.48 μM) and Hsp90α (Kd=0.65 μM) . This tool compound is used in vitro to study endoplasmic reticulum stress and protein folding pathways relevant to cancer and autoimmune disease research.

Product Specifications

Field of Research

Metabolism Research, Pharmacology & Drug Discovery; Cell Biology, Signal Transduction

Smiles

FC (C=C1) =CC=C1CC2=CC=CC=C2CCC3=C (Cl) C (O) =CC (O) =C3C (N[C@@H]4C[C@@H] (O) C4) =O

Molecular Formula

C26H25ClFNO4

Molecular Weight

469.94

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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