Grp94 Inhibitor-2
Grp94 Inhibitor-2 (compound 23) is a cyclopropane-containing small molecule that selectively binds Grp94 (Kd=0.48 μM) and Hsp90α (Kd=0.65 μM) . This tool compound is used in vitro to study endoplasmic reticulum stress and protein folding pathways relevant to cancer and autoimmune disease research.
Product Specifications
Field of Research
Metabolism Research, Pharmacology & Drug Discovery; Cell Biology, Signal Transduction
Smiles
FC (C=C1) =CC=C1CC2=CC=CC=C2CCC3=C (Cl) C (O) =CC (O) =C3C (N[C@@H]4C[C@@H] (O) C4) =O
Molecular Formula
C26H25ClFNO4
Molecular Weight
469.94
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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