M-PEG8-Lys (Mal) -Val-Ala-PAB-Ph-CO-Dazostinag
This compound is an antibody-drug conjugate (ADC) linker-payload featuring a maleimide group for antibody conjugation, a protease-cleavable Val-Ala dipeptide, and a PAB spacer that releases the cytotoxic Dazostinag agent. It is a key research tool for developing targeted cancer therapies and studying drug delivery mechanisms in both in vitro and in vivo experimental models.
Product Specifications
CAS Number
2553413-13-9
Smiles
F[C@H]1[C@H] (N2C=3C (N=C2) =C (NC (=O) C4=C (CN (C (OCC5=CC=C (NC ([C@@H] (NC ([C@@H] (NC ([C@H] (CCCCN6C (=O) C=CC6=O) NC (CCOCCOCCOCCOCCOCCOCCOCCOC) =O) =O) C (C) C) =O) C) =O) C=C5) =O) C) C=CC=C4) N=CN3) O[C@]7 ([C@]1 (OP (=O) (S) OC[C@]8 (O[C@H] ([C@] (OP (=O) (S) OC7) ([C@@H]8O) [H]) N9C%10=C (C (F) =C9) C (=O) N=CN%10) [H]) [H]) [H]
Molecular Formula
C74H98F2N14O27P2S2
Molecular Weight
1779.72
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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