SMARCA2 degrader-20
SMARCA2 degrader-20 is a potent and cell-permeable PROTAC that selectively degrades the SMARCA2 protein. It demonstrates high cellular activity with a DC50 below 100 nM in A549 lung cancer cells, making it a valuable chemical probe for studying SMARCA2 biology and targeted protein degradation in oncology research.
Product Specifications
CAS Number
2568273-85-6
Field of Research
Neuroscience
Smiles
O=C1N (C (=O) C=2C1=CC (NC[C@@H]3CC[C@@H] (CC3) N4CCC (CC4) N5C=C (C=N5) C=6C=C (N=NC6N) C7=C (O) C=CC=C7) =CC2) C8C (=O) NC (=O) CC8
Molecular Formula
C38H41N9O5
Molecular Weight
703.79
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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