SHP2-IN-31
SHP2-IN-31 is a potent and selective wild-type SHP2 inhibitor (IC50 = 13 nM) that suppresses pERK in tumor cells and demonstrates in vivo efficacy against RTK/KRAS-driven xenograft models, making it a valuable research tool for studying oncogenic signaling pathways.
Product Specifications
CAS Number
2411321-35-0
Field of Research
Signal Transduction
Smiles
N[C@H]1C2 (CCN (CC2) C3=C (C) C (=O) N (C (C) =N3) C4=C (Cl) C (Cl) =CC=C4) CO[C@H]1C
Molecular Formula
C21H26Cl2N4O2
Molecular Weight
437.36
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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