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SHP2-IN-31

SHP2-IN-31 is a potent and selective wild-type SHP2 inhibitor (IC50 = 13 nM) that suppresses pERK in tumor cells and demonstrates in vivo efficacy against RTK/KRAS-driven xenograft models, making it a valuable research tool for studying oncogenic signaling pathways.

Product Specifications

CAS Number

2411321-35-0

Field of Research

Signal Transduction

Smiles

N[C@H]1C2 (CCN (CC2) C3=C (C) C (=O) N (C (C) =N3) C4=C (Cl) C (Cl) =CC=C4) CO[C@H]1C

Molecular Formula

C21H26Cl2N4O2

Molecular Weight

437.36

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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