KRAS inhibitor-26
KRAS inhibitor-26 (compound 194a) is a potent small molecule targeting the KRAS G12V oncogenic mutant with an IC50 of ≤100 nM. It serves as a valuable research tool for investigating KRAS-driven tumor biology in both cellular assays and in vivo preclinical models.
Product Specifications
CAS Number
3030576-80-5
Field of Research
Pharmacology & Drug Discovery, Signal Transduction
Smiles
C (OC=1N=C2C=3C (N1) =C (F) C (=NC3) C4=C5C (=CC (O) =C4) C=CC (F) =C5CCCC (=O) NCCC6 (CN2CCOC6) [H]) [C@@]78N (C[C@H] (F) C7) CCC8
Molecular Formula
C36H39F3N6O4
Molecular Weight
676.73
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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