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LSD1-IN-34

LSD1-IN-34 is a potent, orally bioavailable dual inhibitor of LSD1 (IC50=4.51 nM) and MAO-A (IC50=18.46 nM) . It suppresses Ang II-induced cardiac fibroblast activation and TGFβ/Smad signaling, demonstrating efficacy in a murine heart failure model with a favorable rat PK profile and low cytotoxicity.

Product Specifications

Field of Research

Epigenetics & Chromatin, Metabolism Research, Neuroscience, Stem Cell & Developmental Biology

Storage Conditions

-20°C

Notes

For research use only.

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