2-Hexynyl-5′-N-ethylcarboxamidoadenosine
2-Hexynyl-5′-N-ethylcarboxamidoadenosine (HENECA) is a selective A2A adenosine receptor agonist. It increases intracellular cAMP, suppresses TNFα-induced MMP-3 release, and promotes Aβ42 production in SH-SY5Y cells, making it a useful tool for studying neuroinflammation and Alzheimer's disease pathology in vitro.
Product Specifications
CAS Number
141018-30-6
Smiles
O[C@H]1[C@H] (N2C=3C (N=C2) =C (N) N=C (C#CCCCC) N3) O[C@H] (C (NCC) =O) [C@H]1O
Molecular Formula
C18H24N6O4
Molecular Weight
388.42
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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