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CK1-IN-2 hydrochloride

CK1-IN-2 hydrochloride is a potent small molecule inhibitor of casein kinase 1 isoforms, demonstrating IC50 values of 123 nM (CK1α), 19.8 nM (CK1δ), 26.8 nM (CK1ε), and 74.3 nM (p38α MAPK) . This compound is a valuable research tool for studying CK1 and p38α signaling roles in circadian rhythms, Wnt/β-catenin pathways, and neurodegenerative disease models in vitro.

Product Specifications

CAS Number

1383377-49-8

Smiles

Cl.O=C1OCC2=NC=CC (C3=CN (N=C3C=4C=CC (F) =CC4) C) =C12

Molecular Formula

C17H13ClFN3O2

Molecular Weight

345.76

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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