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TST1N-224

TST1N-224 is a VraRC inhibitor that disrupts VraRC-DNA complex formation (IC50=60.2 μM, KD=23.4 μM) by targeting the α9-α10 DNA-binding helices. It shows antimicrobial activity against S. aureus strains, particularly VISA (MIC=63 μM), and can resensitize VISA to vancomycin and methicillin in vitro.

Product Specifications

CAS Number

50566-97-7

Smiles

O=S (=O) (O) CCOCC1SSC (COCCS (=O) (=O) O) CSSC1

Molecular Formula

C10H20O8S6

Molecular Weight

460.65

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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