TST1N-224
TST1N-224 is a VraRC inhibitor that disrupts VraRC-DNA complex formation (IC50=60.2 μM, KD=23.4 μM) by targeting the α9-α10 DNA-binding helices. It shows antimicrobial activity against S. aureus strains, particularly VISA (MIC=63 μM), and can resensitize VISA to vancomycin and methicillin in vitro.
Product Specifications
CAS Number
50566-97-7
Smiles
O=S (=O) (O) CCOCC1SSC (COCCS (=O) (=O) O) CSSC1
Molecular Formula
C10H20O8S6
Molecular Weight
460.65
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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