SB 242084 monohydrochloride
SB 242084 monohydrochloride is a potent, selective, and brain-penetrant 5-HT2C receptor antagonist (pKi=9.0) . It elevates VTA dopaminergic neuron activity and accumbal dopamine release, while also enhancing mitochondrial gene expression via 5-HT2A receptors. This profile supports its research utility in studying depression, anxiety, schizophrenia, and metabolic aspects of acute organ injury.
Product Specifications
CAS Number
1260505-34-7
Smiles
Cl.O=C (NC1=CN=C (OC2=CC=CN=C2C) C=C1) N3C4=CC (Cl) =C (C=C4CC3) C
Molecular Formula
C21H20Cl2N4O2
Molecular Weight
431.32
Storage Conditions
-20°C
Notes
For research use only.
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