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JAK2/FLT3-IN-3

JAK2/FLT3-IN-3 (11r) is a potent and selective dual inhibitor of FLT3 (IC50=0.51 nM) and JAK2 (IC50=2.01 nM) . It demonstrates pro-apoptotic and anticancer activity in cellular assays, making it a useful chemical probe for researching hematological malignancies in vitro.

Product Specifications

CAS Number

3038183-53-5

Field of Research

Epigenetics & Chromatin; Cell Biology

Smiles

O=C (NC1=CC=C (C=C1) C (=O) C) N2CCN (C3=NC (=NC=C3C) NC4=CC=C (C=C4) N5CCC (N6CCN (C) CC6) CC5) CC2

Molecular Formula

C34H45N9O2

Molecular Weight

611.78

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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