LY2023-001
LY2023-001 is a potent and selective G2019S LRRK2 kinase inhibitor, exhibiting an IC50 of 12.9 nM through stable interactions with residues Glu1948 and Ala1950. This small molecule is a valuable research tool for investigating LRRK2-driven pathologies, such as Parkinson's disease, in both cellular and animal models.
Product Specifications
CAS Number
327031-30-1
Smiles
OC=1C (OC) =CC (C=NNC=2N=NC3=C (N2) NC4=CC=C (C=C34) C) =CC1OC
Molecular Formula
C19H18N6O3
Molecular Weight
378.39
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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