HPK1-IN-49
HPK1-IN-49 (Compound I-4) is a small molecule inhibitor of Hematopoietic Progenitor Kinase 1 (HPK1) with an IC50 >100 nM. This compound is a useful research tool for investigating HPK1 function in immune cell signaling and T-cell activation in both in vitro and in vivo experimental contexts.
Product Specifications
CAS Number
2845144-97-8
Field of Research
Signal Transduction
Smiles
N (C1=C2C (=C (C=N1) C=3N4C (=NC3) C=C (F) C=C4) CNC2=O) C5=CC=C (C=C5) N6C[C@@H] ([C@@] (C) (C) O) CCC6
Molecular Formula
C28H29FN6O2
Molecular Weight
500.57
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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