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PROTAC BRD4 Degrader-5-CO-PEG3-N3

PROTAC BRD4 Degrader-5-CO-PEG3-N3 is a clickable reagent featuring the BRD4-targeting molecule GNE-987 conjugated to an azide-terminated PEG linker. It enables modular PROTAC assembly via CuAAC or SPAAC click chemistry, facilitating targeted protein degradation studies in chemical biology and drug discovery research both in vitro and in cellular models.

Product Specifications

CAS Number

2704602-92-4

Field of Research

Epigenetics & Chromatin, Epigenetics & Chromatin; Cell Biology, Pharmacology & Drug Discovery

Purity

99.17% (May vary between batches)

Smiles

CC=1C2=C (N3C ([C@H] (CC (NCCOCCOCCOCC (N[C@H] (C (=O) N4[C@H] (C (N[C@@H] (C) C5=CC=C (C=C5) C6=C (C) N=CS6) =O) C[C@@H] (OC (COCCOCCOCCN=[N+]=[N-]) =O) C4) [C@@] (C) (C) C) =O) =O) N=C2C7=CC=C (Cl) C=C7) =NN=C3C) SC1C

Molecular Formula

C58H75ClN12O12S2

Molecular Weight

1231.87

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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