Exatecan Intermediate 5
Exatecan Intermediate 5 is a key synthetic precursor for the potent topoisomerase I inhibitor Exatecan (DX-8951, IC50 = 2.2 μM) . This compound is utilized in cancer research for in vitro cytotoxicity studies and serves as a critical building block in the construction of targeted Antibody-Drug Conjugates (ADCs) .
Product Specifications
CAS Number
143655-70-3
Field of Research
Pharmacology & Drug Discovery
Smiles
O=C (NC1=CC (F) =C (C2=C1C (=O) C (NC (=O) C) CC2) C) C
Molecular Formula
C15H17FN2O3
Molecular Weight
292.31
Storage Conditions
-20°C
Notes
For research use only.
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