Ganoderic acid A (Standard)

Ganoderic acid A (Standard) is the analytical standard of Ganoderic acid A. This product is intended for research and analytical applications. Ganoderic acid A can inhibit of the JAK-STAT3 signaling pathway, also inhibit proliferation, viability, ROS.

Product Specifications

CAS Number

81907-62-2

UNSPSC

12352211

Target

Apoptosis; Autophagy; Endogenous Metabolite; Reference Standards

Type

Reference Standards

Related Pathways

Apoptosis; Autophagy; Metabolic Enzyme/Protease; Others

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/ganoderic-acid-a-standard.html

Smiles

CC1(C)C(CC[C@]2(C)C3=C([C@@]4([C@@H](O)C[C@@H]([C@]4(CC3=O)C)[C@H](C)CC(C[C@@H](C)C(O)=O)=O)C)[C@@H](O)C[C@@]12[H])=O

Molecular Formula

C30H44O7

Molecular Weight

516.67

References & Citations

[1]Radwan FF et al. Reduction of myeloid-derived suppressor cells and lymphoma growth by a natural triterpenoid. J Cell Biochem. 2015 Jan;116 (1) :102-14.|[2]Yao X et al. Inhibition of the JAK-STAT3 signaling pathway by ganoderic acid A enhances chemosensitivity of HepG2 cells to cisplatin. Planta Med. 2012 Nov;78 (16) :1740-8.|[3]Gill BS et al. Evaluating anti-oxidant potential of ganoderic acid A in STAT 3 pathway in prostate cancer. Mol Biol Rep. 2016 Sep 17.|[4]Shao J et al. [Ganoderic acid A suppresses proliferation and invasion and induces apoptosis in human osteosarcoma cells]. Nan Fang Yi Ke Da Xue Xue Bao. 2015 May;35 (5) :619-24.