Recombinant AURKA Protein

<strong>Recombinant AURKA Protein</strong>_x000D_ <strong>Catalog number:</strong> B2017533_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 20 µg_x000D_ <strong>Molecular Weight or Concentration:</strong> 47 kDa_x000D_ <strong>Supplied as:</strong> Solution_x000D_ <strong>Applications:</strong> a molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> -80°C_x000D_ <strong>Keywords:</strong> Aurora kinase A_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Peng F, Xu J, Cui B, Liang Q, Zeng S, He B, Zou H, Li M, Zhao H, Meng Y, Chen J, Liu B, Lv S, Chu P, An F, Wang Z, Huang J, Zhan Y, Liao Y, Lu J, Xu L, Zhang J, Sun Z, Li Z, Wang F, Lam EW, Liu Q. Oncogenic AURKA-enhanced N(6)-methyladenosine modification increases DROSHA mRNA stability to transactivate STC1 in breast cancer stem-like cells Cell Res. 2021 Mar;31(3):345-361._x000D_ 2: Paulus A, Ailawadhi S, Chanan-Khan A. Novel therapeutic targets in Waldenstrom macroglobulinemia Best Pract Res Clin Haematol. 2016 Jun;29(2):216-228._x000D_ 3: Wang R, Ascanelli C, Abdelbaki A, Fung A, Rasmusson T, Michaelides I, Roberts K, Lindon C. Selective targeting of non-centrosomal AURKA functions through use of a targeted protein degradation tool Commun Biol. 2021 May 28;4(1):640._x000D_ 4: Tiwari S, Pandey VP, Yadav K, Dwivedi UN. Modulation of interaction of BRCA1-RAD51 and BRCA1-AURKA protein complexes by natural metabolites using as possible therapeutic intervention toward cardiotoxic effects of cancer drugs: an in-silico approach J Biomol Struct Dyn. 2022;40(23):12863-12879._x000D_ 5: Dodson CA. Production of Protein Kinases in E. coli Methods Mol Biol. 2017;1586:251-264._x000D_ 6: Sehdev V, Katsha A, Arras J, Peng D, Soutto M, Ecsedy J, Zaika A, Belkhiri A, El-Rifai W. HDM2 regulation by AURKA promotes cell survival in gastric cancer Clin Cancer Res. 2014 Jan 1;20(1):76-86._x000D_ 7: Chen TC, Liu YW, Huang YH, Yeh YC, Chou TY, Wu YC, Wu CC, Chen YR, Cheng HC, Lu PJ, Lai JM, Huang CY. Protein phosphorylation profiling using an in situ proximity ligation assay: phosphorylation of AURKA-elicited EGFR-Thr654 and EGFR-Ser1046 in lung cancer cells PLoS One. 2013;8(3):e55657._x000D_ 8: Dar AA, Belkhiri A, El-Rifai W. The aurora kinase A regulates GSK-3beta in gastric cancer cells Oncogene. 2009 Feb 12;28(6):866-75._x000D_ 9: Lee KB, Jin H, Ye S, Park BH, Kim SM. Recombinant human bone morphogenetic protein-2 inhibits gastric cancer cell proliferation by inactivating Wnt signaling pathway via c-Myc with aurora kinases Oncotarget. 2016 Nov 8;7(45):73473-73485._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/23333597">10: Li L, Yang G, Ren C, Tanimoto R, Hirayama T, Wang J, Hawke D, Kim SM, Lee JS, Goltsov AA, Park S, Ittmann MM, Troncoso P, Thompson TC. Glioma pathogenesis-related protein 1 induces prostate cancer cell death through Hsc70-mediated suppression of AURKA and TPX2 Mol Oncol. 2013 Jun;7(3):484-96. </a>_x000D_ _x000D_ <strong>Products Related to Recombinant AURKA Protein can be found at</strong> <a href="https://moleculardepot.com/product-category/Proteins/"> Proteins</a>