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TQ05310

TQ05310 is a potent, orally bioavailable inhibitor of mutant IDH2 (R140Q and R172K), suppressing oncogenic 2-HG production. It induces cellular differentiation and is a key research tool for studying mutant IDH2-driven pathologies, including acute myeloid leukemia, in both in vitro and in vivo models.

Product Specifications

CAS Number

2071196-10-4

Field of Research

Metabolism Research

Smiles

FC (F) (F) C1=NC (=CC=C1) C2=NC (=NOC (C) (C) C) N=C (N2) NC=3C=CN=C (C3) C (F) (F) F

Molecular Formula

C19H17F6N7O

Molecular Weight

473.38

Storage Conditions

-20°C

Notes

For research use only.

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