TQ05310
TQ05310 is a potent, orally bioavailable inhibitor of mutant IDH2 (R140Q and R172K), suppressing oncogenic 2-HG production. It induces cellular differentiation and is a key research tool for studying mutant IDH2-driven pathologies, including acute myeloid leukemia, in both in vitro and in vivo models.
Product Specifications
CAS Number
2071196-10-4
Field of Research
Metabolism Research
Smiles
FC (F) (F) C1=NC (=CC=C1) C2=NC (=NOC (C) (C) C) N=C (N2) NC=3C=CN=C (C3) C (F) (F) F
Molecular Formula
C19H17F6N7O
Molecular Weight
473.38
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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