PTOTAC HSD17B13 degrader 1
PTOTAC HSD17B13 Degrader 1 is a bifunctional molecule designed to degrade the protein HSD17B13, utilizing a specific ligand for the target, a linker, and an E3 ligase ligand (E3 Ligase Ligand-linker Conjugate 114) . This PROTAC enables the study of HSD17B13's role in metabolic diseases like NAFLD through targeted protein degradation in biochemical and cellular research.
Product Specifications
CAS Number
3046195-01-8
Field of Research
Metabolism Research, Pharmacology & Drug Discovery
Smiles
O=C1N (C=2C (N1C) =CC (CCCN3CC=4C (C3) =CC=C (C4) C5=CC=6C (C=C5) =CN (N6) [C@@H]7CC[C@@H] (CNC (=O) C8=C (F) C (F) =C (O) C (F) =C8) CC7) =CC2) C9C (=O) NC (=O) CC9.Cl
Molecular Formula
C45H45ClF3N7O5
Molecular Weight
856.33
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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