Cbl-b-IN-21
Cbl-b-IN-21 is a small molecule ligand designed for the E3 ubiquitin ligase Cbl-b, utilized in constructing PROTAC degraders for research. It enables targeted protein degradation studies in both cellular and in vivo models to investigate immune regulation and oncology pathways.
Product Specifications
CAS Number
2851878-87-8
Field of Research
Cancer Biology, Pharmacology & Drug Discovery
Smiles
C (F) (F) (F) C=1C=2N (C (=O) N (C2) C3=CC ([C@@H] ([C@H]4CCC4) C=5N (C) C=NN5) =CC=C3) C=C (C=O) C1
Molecular Formula
C23H20F3N5O2
Molecular Weight
455.43
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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