SPI-001
SPI-001 is a potent and selective PPM1D phosphatase inhibitor (IC50=0.48 μM) with demonstrated anticancer activity. It enhances p53 phosphorylation and induces apoptosis in PPM1D-overexpressing breast cancer cells, supporting its use in oncology research for both in vitro and in vivo mechanistic studies.
Product Specifications
CAS Number
1220996-46-2
Field of Research
Cell Biology, Metabolism Research
Smiles
C[C@@]12[C@] ([C@@H] (O[Si] (C (C) (C) C) (C) C) C[C@]3 ([C@]1 (C[C@@H] (C) C[C@H]3O[Si] (CC) (CC) CC) [H]) [H]) ([C@@] (CO) (C) C[C@H] (O) C2) [H]
Molecular Formula
C30H60O4Si2
Molecular Weight
540.97
Storage Conditions
-20°C
Notes
For research use only.
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