A-1208746
A-1208746 is a potent, selective MCL-1 inhibitor (Ki = 0.454 nM) that induces apoptosis via caspase-3/7 activation and loss of mitochondrial membrane potential in vitro. It demonstrates synergistic activity with Navitoclax, supporting its application in oncology research for studying hematological and solid tumor models.
Product Specifications
CAS Number
1668553-23-8
Field of Research
Cell Biology
Smiles
O=C (O) C1=C (C=2C=CC=C (C=3C (=NN (C3COC4=CC=C (C=C4) N5CCN (CC5) S (=O) (=O) C) C) C) C2N1CCN6CCOCC6) CCCOC7=CC=CC=8C=CC=CC78
Molecular Formula
C45H52N6O7S
Molecular Weight
821
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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