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Sigma-1 receptor antagonist 6

Compound 12 is a potent and selective Sigma-1 receptor (σ1R) antagonist. It exhibits significant antiallodynic efficacy in vivo, effectively reversing mechanical allodynia in rodent models of paclitaxel-induced neuropathic pain, supporting its use in neuroscience and analgesic research.

Product Specifications

CAS Number

1335032-28-4

Field of Research

Pharmacology & Drug Discovery

Smiles

N#CC1=C (N=C (C (C#N) =C1C=2C=CC=CC2) N (C) CC#C) NCCCC3CCN (CC=4C=CC=CC4) CC3

Molecular Formula

C32H34N6

Molecular Weight

502.65

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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