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AURKA against 1

Compound Ac13 (AURKA inhibitor 1) is a potent and selective Aurora kinase A (AURKA) inhibitor with sub-nanomolar IC50. It suppresses tumor cell proliferation by targeting the acetylation of endogenous lysine K162, a modification reversibly regulated by SIRT3 in cellular models like HCT116. This inhibitor is a valuable tool for studying AURKA signaling in cancer research.

Product Specifications

Field of Research

Cell Biology, Epigenetics & Chromatin, Signal Transduction

Molecular Formula

C28H32FN9O2

Molecular Weight

545.61

Storage Conditions

-20°C

Notes

For research use only.

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