AURKA against 1
Compound Ac13 (AURKA inhibitor 1) is a potent and selective Aurora kinase A (AURKA) inhibitor with sub-nanomolar IC50. It suppresses tumor cell proliferation by targeting the acetylation of endogenous lysine K162, a modification reversibly regulated by SIRT3 in cellular models like HCT116. This inhibitor is a valuable tool for studying AURKA signaling in cancer research.
Product Specifications
Field of Research
Cell Biology, Epigenetics & Chromatin, Signal Transduction
Molecular Formula
C28H32FN9O2
Molecular Weight
545.61
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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