A-1248767
A-1248767 is a potent and selective MCL-1 inhibitor (IC50=23.9 nM; Ki=0.41 nM) derived from A-1210477. It exhibits high-affinity binding, induces intracellular MCL-1 protein stabilization, and triggers apoptosis in cancer cells, supporting its use in oncology research for in vitro and in vivo mechanistic and therapeutic studies.
Product Specifications
CAS Number
2228052-38-6
Field of Research
Cell Biology
Smiles
O=C (O) C1=C (C=2C=CC=C (C=3C (=NN (C3C) C) COC4=CC=C (C=C4) N5CCN (C (=O) N (C) C) CC5) C2N1CCN6CCOCC6) CCCOC7=CC=CC=8C=CC=CC78
Molecular Formula
C47H55N7O6
Molecular Weight
813.98
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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