CSN5-IN-1
CSN5-IN-1 (Ac-11) is a CSN5 inhibitor with IC50 values of 12.56 μM (FP assay) and 19 μM (fluorescence assay) . It modulates cellular protein levels, reducing PD-L1 and increasing NEDD8-Cul1, making it a useful probe for studying COP9 signalosome function in cancer immunology and protein neddylation pathways.
Product Specifications
Field of Research
Cell Biology, Immunology & Inflammation, Neuroscience, Protein Biochemistry
Molecular Formula
C17H22N2O2S
Molecular Weight
318.43
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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