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CSN5-IN-1

CSN5-IN-1 (Ac-11) is a CSN5 inhibitor with IC50 values of 12.56 μM (FP assay) and 19 μM (fluorescence assay) . It modulates cellular protein levels, reducing PD-L1 and increasing NEDD8-Cul1, making it a useful probe for studying COP9 signalosome function in cancer immunology and protein neddylation pathways.

Product Specifications

Field of Research

Cell Biology, Immunology & Inflammation, Neuroscience, Protein Biochemistry

Molecular Formula

C17H22N2O2S

Molecular Weight

318.43

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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