SMARCA2 degrader-17
SMARCA2 degrader-17 is a small molecule that selectively degrades the SMARCA2 protein. It demonstrates synergistic anti-proliferative activity with Adagrasib in vitro and has shown efficacy in inhibiting tumor growth in vivo, making it a valuable tool for oncology research targeting SWI/SNF chromatin remodeling complexes.
Product Specifications
CAS Number
2755761-78-3
Field of Research
Epigenetics & Chromatin, Neuroscience
Smiles
OC1=C (C=2C=C3N4[C@] (CN (CC4) [C@H]5CN (C[C@@H] (OC=6C=C ([C@H] (C (=O) N7[C@H] (C (N[C@@H] (C) C8=CC=C (C=C8) C9=C (C) N=CS9) =O) C[C@@H] (O) C7) [C@@H] (C) C) ON6) C) CC5) (CNC3=NN2) [H]) C=CC=C1
Molecular Formula
C47H58N10O6S
Molecular Weight
891.09
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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