VEGFR-2-IN-52
VEGFR-2-IN-52 (14d) is a potent VEGFR-2 inhibitor (IC50: 191.1 nM) that suppresses downstream signaling proteins like p-VEGFR-2, MMP9, p-ERK1/2, and p-MEK1. It exerts cytotoxic effects by inducing apoptosis, causing G0/G1 cell cycle arrest, and elevating ROS levels, making it a useful tool for angiogenesis and oncology research in vitro.
Product Specifications
CAS Number
3046428-94-5
Field of Research
Cardiovascular Research, Cardiovascular Research; Cell Biology, Cell Biology, Immunology & Inflammation, Metabolism Research, Signal Transduction
Smiles
O=C (N) C1=C (SC=C1C=2C=CC (Cl) =CC2) NC (=O) NCCCCN3CCCC3
Molecular Formula
C20H25ClN4O2S
Molecular Weight
420.96
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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