Evo312
Evo312 is a dose-dependent PKCβI inhibitor (IC50 = 117.34 nM) that suppresses PKCβI protein expression, inducing cell cycle arrest and apoptosis. It demonstrates potent antiproliferative activity in pancreatic cancer cells, including gemcitabine-resistant lines, and shows antitumor efficacy in mouse xenograft models.
Product Specifications
CAS Number
2820245-53-0
Field of Research
Cell Biology, Epigenetics & Chromatin, Signal Transduction
Smiles
O=C (OC=1C=CC=2NC3=C (C2C1) CCN4C (=O) C=5C=CC=CC5N (C) C34) C
Molecular Formula
C21H19N3O3
Molecular Weight
361.39
Storage Conditions
-20°C
Notes
For research use only.
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