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SP100030 analogue 1

SP100030 analogue 1 (compound 11) is a selective SITA inhibitor that blocks XPO1-mediated IL2 upregulation, exhibiting an EC50 of 137 nM in Jurkat IL2-Luc reporter assays. This tool compound is used in vitro to study nuclear export and T-cell activation pathways in immunology and oncology research.

Product Specifications

CAS Number

154934-68-6

Field of Research

Pharmacology & Drug Discovery

Smiles

O=C (NC1=CC (F) =CC (=C1) C (F) (F) F) C2=CN=C (Cl) N=C2C (F) (F) F

Molecular Formula

C13H5ClF7N3O

Molecular Weight

387.64

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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