SP100030 analogue 1
SP100030 analogue 1 (compound 11) is a selective SITA inhibitor that blocks XPO1-mediated IL2 upregulation, exhibiting an EC50 of 137 nM in Jurkat IL2-Luc reporter assays. This tool compound is used in vitro to study nuclear export and T-cell activation pathways in immunology and oncology research.
Product Specifications
CAS Number
154934-68-6
Field of Research
Pharmacology & Drug Discovery
Smiles
O=C (NC1=CC (F) =CC (=C1) C (F) (F) F) C2=CN=C (Cl) N=C2C (F) (F) F
Molecular Formula
C13H5ClF7N3O
Molecular Weight
387.64
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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