ONC213
ONC213 is a small molecule inhibitor of α-ketoglutarate dehydrogenase (αKGDH) used in acute myeloid leukemia (AML) research. It suppresses mitochondrial respiration, increases α-ketoglutarate levels, and induces apoptosis in AML cells, as demonstrated in in vitro studies.
Product Specifications
CAS Number
1977540-13-8
Field of Research
Cell Biology
Smiles
O=C1C2=C (N3C (=NCC3) N1CC4=CC=C (F) C (F) =C4) CCN (CC=5C=CC=CC5) C2
Molecular Formula
C23H22F2N4O
Molecular Weight
408.44
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
More Discoveries
Explore Other Products
Browse additional items from our catalog
RC229060L3V 200 µL
POLR3B (NM_001160708) Human Tagged ORF Clone Lentiviral Particle
Sign In for Pricing
View Details 
126502 50 µg
EXOC5 (Exocyst Complex Component Sec10, hSec10, Exocyst Complex Component 5, SEC10, SEC10L1)
Sign In for Pricing
View Details MBS1438970-01 0.02 mg (Yeast)
Recombinant Mouse Cytochrome P450 2C70 (Cyp2c70)
Sign In for Pricing
View Details 
MBS1438970-02 0.1 mg (Yeast)
Recombinant Mouse Cytochrome P450 2C70 (Cyp2c70)
Sign In for Pricing
View Details