ONC213
ONC213 is a small molecule inhibitor of α-ketoglutarate dehydrogenase (αKGDH) used in acute myeloid leukemia (AML) research. It suppresses mitochondrial respiration, increases α-ketoglutarate levels, and induces apoptosis in AML cells, as demonstrated in in vitro studies.
Product Specifications
CAS Number
1977540-13-8
Field of Research
Cell Biology
Smiles
O=C1C2=C (N3C (=NCC3) N1CC4=CC=C (F) C (F) =C4) CCN (CC=5C=CC=CC5) C2
Molecular Formula
C23H22F2N4O
Molecular Weight
408.44
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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