Elubrixin tosylate
Elubrixin (SB-656933) is a potent, selective, competitive and reversible CXCR2 antagonist; inhibits CXCL1-induced CD11b up-regulation on PMNs in an in vitro whole blood assay and to be active in in vivo rodent inhalation challenge models of airway inflammation that used endotoxin and ozone to induce airway neutrophilia.Fibrosis Phase 2 Discontinued.
Product Specifications
CAS Number
960495-43-6
Product Name Alternative
SB-656933
Purity
>98% (HPLC)
Solubility
In Vitro: DMSO : 125 mg/mL (196.69 mM)
Smiles
CC1=CC=C (C=C1) S (=O) (=O) O.C1CN (CCN1) S (=O) (=O) C2=C (C=CC (=C2O) NC (=O) NC3=C (C (=CC=C3) F) Cl) Cl
Molecular Formula
C24H25Cl2FN4O7S2
Molecular Weight
635.503
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
1- (2-chloro-3-fluorophenyl) -3- (4-chloro-2-hydroxy-3-piperazin-1-ylsulfonylphenyl) urea tosylate
Available Sizes
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