Hydroxy-PEG10-acid

Hydroxy-PEG10-acid (HO-PEG10-CH2CH2COOH) is a PEG-based non-cleavable ADC linker that can be used in the synthesis of Antibody-Drug Conjugates (ADCs) [1].

Product Specifications

CAS Number

[2375611-66-6]

Product Name Alternative

HO-PEG10-CH2CH2COOH

UNSPSC

12352203

Hazard Statement

H302, H315, H319, H335

Target

ADC Linker

Type

ADC Related

Related Pathways

Antibody-drug Conjugate/ADC Related

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/hydroxy-peg10-acid.html

Purity

99.59

Solubility

10 mM in DMSO

Smiles

O=C(O)CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCO

Molecular Formula

C23H46O13

Molecular Weight

530.60

Precautions

H302, H315, H319, H335

References & Citations

[1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562