Sauristolactam
Product Specifications
UNSPSC Description
Sauristolactam, a natural aristolactam isolated from aerial portions of Saururus chinensis, has significant neuroprotective activity against glutamate-induced toxicity in primary cultured rat cortical cells[1]. Sauristolactam also inhibits the receptor activator of nuclear factor-κB ligand (RANKL)-induced osteoclastogenesis and has the potential to inhibit osteoclast differentiation[2].
Target Antigen
Others
Type
Natural Products
Related Pathways
Others
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/Sauristolactam.html
Solubility
10 mM in DMSO
Smiles
O=C1N(C2=C3C1=CC(O)=C(C3=C4C(C=CC=C4)=C2)OC)C
Molecular Weight
279.29
References & Citations
[1]Kim SR, et al. Aristolactam BII of Saururus chinensis attenuates glutamate-induced neurotoxicity in rat cortical cultures probably by inhibiting nitric oxide production. Planta Med. 2004 May;70(5):391-6.|[2]Li Z, et al. Saurolactam Inhibits Proliferation, Migration, and Invasion of Human Osteosarcoma Cells. Cell Biochem Biophys. 2015 Jul;72(3):719-26.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-118482/Sauristolactam-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-118482/
Clinical Information
No Development Reported
CAS Number
128533-02-8
Available Sizes
Curated Selection
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