Anavex-2-73
Anavex2-73 is a muscarinic/σ1 ligand. ANAVEX2-73 (0.01-3.0 mg/kg i.p.) alleviated the scopolamine- and dizocilpine-induced learning impairments. ANAVEX2-73 (300 μg/kg) also reversed the learning deficits in mice injected with Aβ (25-35) peptide, a non-transgenic Alzheimer's disease model. The neuroprotective activity of ANAVEX2-73, its mixed cholinergic/σ (1) activity, its low active dose range and its long duration of action together reinforce its therapeutic potential in Alzheimer's disease.
Product Specifications
CAS Number
195615-84-0
Purity
>98%
Smiles
Cl[H].O1C ([H]) ([H]) C ([H]) ([H]) C ([H]) (C ([H]) ([H]) N (C ([H]) ([H]) [H]) C ([H]) ([H]) [H]) C1 (C1C ([H]) =C ([H]) C ([H]) =C ([H]) C=1[H]) C1C ([H]) =C ([H]) C ([H]) =C ([H]) C=1[H]
Molecular Formula
C19H24CLNO
Molecular Weight
317.853
Notes
For research use only.
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