OBX02-011
OBX02-011 is a potent, reversible, fourth-generation EGFR tyrosine kinase inhibitor (TKI) that overcomes the EGFR C797S mutation, inhibits triple mutants Del19/T790M/C797S and L858R/T790M/C797S with IC50 of 0.134 and 2.09 nM, respectively.
Product Specifications
CAS Number
2349336-18-9
Purity
>98%
Smiles
ClC1C=NC (=NC=1NC1C=CC=CC=1N (C) S (C) (=O) =O) NC1C=CC (=CC=1OC) N1CCC (CC1) N1CCN (C) CC1
Molecular Formula
C29H39CLN8O3S
Molecular Weight
615.189763307571
Notes
For research use only.
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