SMAD2, Human (His-SUMO)
SMAD2 protein, an R-SMAD, acts as a transcriptional modulator activated by TGF-beta and activin type 1 receptor kinases. It binds TRE elements, regulating TGF-beta target genes. Forming a complex with SMAD4, it promotes transcription, positively regulating PDPK1 and showing potential tumor suppressor functions in colorectal carcinoma. SMAD2 interacts with various proteins, participating in signal transduction and transcriptional regulation. SMAD2 Protein, Human (His-SUMO) is the recombinant human-derived SMAD2 protein, expressed by E. coli , with N-SUMO, N-6*His labeled tag.
Product Specifications
Product Name Alternative
SMAD2 Protein, Human (His-SUMO), Human, E. coli
UNSPSC
12352202
Type
Recombinant Proteins
Assay Protocol
https://www.medchemexpress.com/cytokines/smad2-protein-human-his-sumo.html
Purity
97.00
Smiles
Molecular Formula
4087 (Gene_ID) Q15796-1 (S2-S467) (Accession)
Molecular Weight
Approximately 68.2 kDa, based on SDS-PAGE under reducing conditions.
Shipping Conditions
Room temperature in continental US; may vary elsewhere.
Storage Conditions
Stored at -20°C for 2 years
Scientific Category
Recombinant Proteins
Available Sizes
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