GQN-B37-E
GQN-B37-E is a potent and selective small molecule inhibitor of MCL-1, binding its BH3-binding groove with sub-micromolar affinity (Ki=0.6 μM) while showing minimal activity against BCL-2 or BCL-XL. It is a valuable research tool for studying apoptosis and MCL-1-dependent cancer mechanisms in both cellular and biochemical assays.
Product Specifications
CAS Number
2982663-28-3
Field of Research
Cell Biology
Smiles
C (=C/C (N[C@@H] (CC=1C=2C (NC1) =CC=CC2) C (O) =O) =O) \C=3C (=NN (C3) C4=CC (Cl) =CC=C4) C5=CC=C (O) C=C5
Molecular Formula
C29H23ClN4O4
Molecular Weight
526.97
Storage Conditions
-20°C
Notes
For research use only.
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