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COB-187

COB-187 is a potent, selective, and ATP-competitive GSK-3β inhibitor that acts via reversible engagement of Cys-199. This small molecule has demonstrated utility in cellular research, suppressing LPS-induced cytokine and SARS-CoV-2 spike protein-triggered CXCL10 production in vitro.

Product Specifications

CAS Number

1862177-86-3

Field of Research

Signal Transduction, Stem Cell & Developmental Biology

Smiles

S=C1SCC (O) (C=2C=CC=CC2) N1CC=3C=CN=CC3

Molecular Formula

C15H14N2OS2

Molecular Weight

302.41

Storage Conditions

-20°C

Notes

For research use only.

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