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RWJ-58643

RWJ-58643 is a β-trypsin and trypsin inhibitor for research on allergic inflammation. In vivo studies show it reduces nasal symptoms and IL-5 at 100 mg, but exhibits a paradoxical, dose-dependent increase in eosinophils and IL-5 at higher doses (300-600 mg) .

Product Specifications

CAS Number

287183-00-0

Field of Research

Protein Biochemistry

Smiles

C (C (NC (=O) [C@H]1N (C (C) =O) C[C@H] (O) C1) CCCNC (=N) N) (=O) C2=NC=3C (S2) =CC=CC3

Molecular Formula

C20H26N6O4S

Molecular Weight

446.52

Storage Conditions

-20°C

Notes

For research use only.

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