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KSI-6666

KSI-6666 is a potent and orally bioavailable competitive antagonist of the S1PR1 receptor, demonstrating an IC50 of 6.4 nM. It has shown efficacy in preclinical models of autoimmune diseases, including encephalomyelitis and T-cell transfer colitis, highlighting its utility for immunology and inflammation research.

Product Specifications

CAS Number

1807873-14-8

Field of Research

Pharmacology & Drug Discovery

Smiles

O=C (O) C1CN (CC2=CC (=CC=C2C) C (N (C3=CC=C (Cl) C (=C3) C (F) (F) F) CC) C) C1

Molecular Formula

C23H26ClF3N2O2

Molecular Weight

454.91

Storage Conditions

-20°C

Notes

For research use only.

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