KSI-6666
KSI-6666 is a potent and orally bioavailable competitive antagonist of the S1PR1 receptor, demonstrating an IC50 of 6.4 nM. It has shown efficacy in preclinical models of autoimmune diseases, including encephalomyelitis and T-cell transfer colitis, highlighting its utility for immunology and inflammation research.
Product Specifications
CAS Number
1807873-14-8
Field of Research
Pharmacology & Drug Discovery
Smiles
O=C (O) C1CN (CC2=CC (=CC=C2C) C (N (C3=CC=C (Cl) C (=C3) C (F) (F) F) CC) C) C1
Molecular Formula
C23H26ClF3N2O2
Molecular Weight
454.91
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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