NH2-PEG3-VC-PAB-MMAE
NH2-PEG3-VC-PAB-MMAE is a cleavable drug-linker conjugate designed for constructing antibody-drug conjugates (ADCs) . It incorporates the cytotoxic payload MMAE, enabling targeted delivery and release in both in vitro and in vivo cancer research models to study ADC efficacy and mechanism.
Product Specifications
CAS Number
2641442-97-7
Field of Research
Cell Biology, Signal Transduction
Smiles
[C@H] ([C@H] (C (N[C@@H] ([C@@H] (O) C1=CC=CC=C1) C) =O) C) (OC) [C@]2 (N (C (C[C@H] ([C@@H] (N (C ([C@@H] (NC ([C@@H] (N (C (OCC3=CC=C (NC ([C@@H] (NC ([C@@H] (NC (COCCOCCOCCN) =O) [C@H] (C) C) =O) CCCNC (N) =O) =O) C=C3) =O) C) C (C) C) =O) [C@H] (C) C) =O) C) [C@H] (CC) C) OC) =O) CCC2) [H]
Molecular Formula
C66H109N11O16
Molecular Weight
1312.64
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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